Two Readouts.
One Complete Picture.
Unlock a holistic spatial view with complementary RNA and protein data, illuminating biology from early discovery to late-stage development.
Benefits of Complementary Datasets
Reveal Biology in True Context
Build RNA maps or protein signatures to see cell types, states, and interactions in situ.
Move From Hypothesis to Discovery
Start with broad discovery using large MERSCOPE Ultra panels, then validate with targeted protein markers.
Keep Tissue Architecture Intact
Preserve morphology in fresh frozen and FFPE tissue; align RNA and protein readouts on matched/adjacent sections for in-place biological context.
Flexible Panels and Assay Targets
Use ready-to-run gene panels and validated antibody assays, or fully customize panels to your biology and tissue type.
Imaging to Insights
AI-enabled image analysis and intuitive visualization software help convert spatial data into decisions.
Built for Confidence
Pathology-grade proteomics, single-cell transcriptomics, and rigorous workflows support reliable results for research and drug discovery.
Choose Your Starting Point
Begin with transcriptomics or proteomics; compare with the other in downstream analysis when needed.
Spatial transcriptomics maps RNA at subcellular resolution, while multiplex spatial proteomics quantifies protein expression with pathology-grade rigor.
Each modality can stand alone to answer targeted questions. When additional context is needed, run the second readout on matched or adjacent sections to align targets and preserve tissue architecture.
Start with MERSCOPE™ Ultra and explore results in Vizualizer™ for RNA. Or run OmniVUE® or U-VUE® protein kits and analyze with STARVUE™. Optionally interrogate proteins on matched sections to confirm what transcripts predict, keeping established FFPE and fresh-frozen workflows while increasing confidence.
MERSCOPE™ Ultra Imaging
High-throughput imaging purpose-built for MERFISH experiments with speed, sensitivity, and reproducibility for discovery-scale studies.
Gene Panels & Reagents
Ready-to-run content plus custom options; supported by validated reagents and consumables optimized for performance.
Vizualizer™ Analysis
Explore and share spatial results with segmentation, clustering, differential expression, and figure export; AI-powered analytics accelerate interpretation.
Core Biomarker Panels
Pre-optimized OmniVUE™ Core Panels deliver high-sensitivity, pathology-grade proteomics biomarker data. Ready to use for fast, reproducible spatial discovery.
Custom Biomarker Panels
U-VUE® Panels let you design custom or semi-custom biomarker assays using InSituPlex® technology for ultra-sensitive, AI-guided spatial discovery tailored to your biology.
STARVUE™
AI-enhanced multiplex spatial proteomics powered by InSituPlex® technology. Visualize and quantify protein signatures in context for translational and clinical research confidence.
Which Path is Right for You?
What it measures
Thousands of RNA targets via MERFISH 2.0 for single-cell, subcellular maps.
Multiplex immunofluorescence quantifying protein abundance/localization in tissue.
Correlate transcriptional programs with protein expression on matched/serial sections.
Best for
Cell typing, state discovery, pathway inference.
Target validation, pathway activity, and morphology-aware phenotyping.
Confirm mechanisms and phenotypes with orthogonal evidence.
Sample types
Fresh frozen, fixed frozen, FFPE, cultured cells, and more.
Fresh frozen and FFPE.
Adjacent/serial sections from the same block to align ROIs.
Resolution & output
Subcellular RNA locations; per-cell counts; segmentation, clustering, DE genes.
Multiplexed protein intensity/positivity per cell/region; morphology preserved.
Co-interpreted cell types/neighborhoods; region-level RNA–protein correlations.
Targets & panels
Ready-to-run or custom gene panels.
Validated antibody panels/kits or fully custom.
Align gene lists with antibody markers to test and validate hypotheses.
Example product lines
MERSCOPE Ultra, MERSCOPE Vizualizer, Gene Panels, Imagine Kits, etc.
OmniVUE, U-VUE, STARVUE.
Workflow tip: Start with one readout; add the other on matched sections for higher confidence without changing FFPE workflows.
