Application Areas

MERFISH is a game-changing technology in single-cell genomics and has broad applications in both fundamental biology and medicine, ranging from basic science, to drug discovery, to clinical pathology. Given its ability to quantify RNAs across a wide range of abundances while preserving native context, MERFISH enables many applications of in situ transcriptomic analyses of individual cells in culture or complex tissues.

Oncology

Immunology

Neuroscience

Infectious Disease

Development Biology & Regenerative Medicine

Learn more about how Vizgen technology can be applied to your research

Spatially profile gene expression across whole tissues

Vizgen’s imaging platform reveals the distribution of transcriptome-wide gene expression across tissues slices. With unprecedented accuracy, our measurement enables unique insight into the molecular composition of complex biological systems.

Resolve individual transcripts with nanometer-scale resolution

Every Vizgen measurement resolves the position of each detected transcript with sub-micron accuracy, providing access to the intracellular organization of the transcriptome within every cell. Critically, these measurements are available for every cell across centimeter-scale tissue samples.

Discover and Map Novel Cell Types and States

Vizgen measurements produce single-cell expression profiles that can be used to define cell types and states. The identify of every cell can be mapped back to the spatial coordinates within tissue samples, providing a detailed map of the organization of the tissue and precisely defining the cellular microenvironment experienced by every cell in the sample.

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