In-house Spatial Transcriptomics
In-house Spatial Transcriptomics
In-house Laboratory Services
Vizgen’s MERSCOPE® Platform offers an unprecedented view of the spatial organization of biological systems and will help enable researchers looking to gain deeper insights into a wide range of biological domains, from fundamental biology through translational medicine. Leverage our in-house sample processing and MERFISH spatial profiling expertise to accelerate your scientific research and yield fundamental insights faster. Vizgen offers flexible custom projects and proof of principle projects. Demand is high, start planning your project today.
- Receive expert guidance and support from initial project consultation to data delivery.
- Gain access to MERFISH data without constraints on your own lab resources.
- Leverage the high-quality MERFISH data in your research and manuscripts.
Experience MERFISH with Ease and Expertise
Comprehensive Spatial Genomic Profiling
MERSCOPE uses MERFISH technology to directly map and quantify the spatial distribution of RNA and proteins in your tissue samples.
High-quality Spatial Genomics Data Generation
MERSCOPE’s combination of optimized optics and MERFISH technology generates high resolution and high-quality spatial genomics data that will provide unique biological insights to help your lab decode biological complexity with confidence.
Access to Vizgen’s Scientific Expertise
Vizgen’s Lab Services team is comprised of scientists with a wide range of demonstrated knowledge in cell and molecular biology, single-cell genomics, and imaging technologies, along with computational biologists and project managers to oversee data analysis and project execution. Vizgen offers the greatest depth of MERFISH expertise and instrument operation experience available.
Our Offerings
Custom Lab Services
Excited to get your hands on MERFISH data generated on the MERSCOPE® Platform, but have limited resources in your lab or time constraints for data generation? Custom projects allow you to work with our lab services team to design a project that fits your research needs.
Our MERFISH experts will:
- Optimize a custom designed gene panel specific to your species and research application.
- Develop and validate a protocol for your species and sample type.
- Deliver high-quality MERFISH data for your team to analyze.
Spatial Profiling Lab Service Project Details
Project Workflow
Meet with our team to discuss your project in detail and receive a statement of work.
We assist with selecting the gene panel and protein co-detection strategy most relevant for each biological question and optimize for your species and tissue type or help you choose a predefined panel.
Ship your samples to our laboratory headquartered in Cambridge, MA
We develop a sample processing and MERFISH protocol specific to custom project samples or use a standard protocol for POP studies.
Our team spatially profiles the gene and protein expression of your tissue samples with MERSCOPE. Vizgen scientists have access to the largest centralized collection of MERSCOPE instruments enabling a rapid turn-a-round of high-quality data.
You receive decoded MERFISH datasets packaged into easy-to-read tables and high-resolution images to analyze along with a final report.
“Using MERFISH technology, researchers at the Allen Institute were able to gather cellular-resolution spatial transcriptomic data that advanced us significantly closer toward our goal of creating a taxonomy of cell types and a description of their connectivity within brain circuits – laying the groundwork to one day understanding how brain circuits function.
In the hands of the research community, I believe that MERSCOPE will be a powerful tool for standardizing the way we characterize different cell types, not just in the brain, but also in the rest of the body, ultimately bringing a deeper level of understanding to all life science research .”
Hongkui Zeng, Ph.D.
Executive VP & Director of the Allen Institute for Brain ScienceApplications
Neuroscience
Spatially profile the gene expression of whole tissue sections down to the sub-cellular level to accurately characterize cells within the brain. Detect low and high abundance genes to create complete molecular cell atlases.
Oncology
Investigate the tumor microenvironment by identifying novel cell-cell communication and interactions between cancer cells and immune cells. Unlock high-quality spatial genomics data from FFPE tissue sections.
Kidney Disease
Preserve and explore the spatial architecture of complex tissues to understand the structure-function relationships of cells and disease pathophysiology. Visualize spatial gene expression to discover and map new cell types and states.
