Publications
Wenfei Sun, Zhihui Liu, Xian Jiang, Michelle B. Chen, Hua Dong, Jonathan Liu, Thomas C. Sudhof, Stephen R. Quake
bioRxiv (2023)
Abstract Memory encodes past experiences, thereby enabling future plans. The basolateral amygdala (BLA) is a center of salience networks that underlie emotional experience and thus plays a key role in long-term fear memory formation. Here…
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Safety Data Sheets
Safety Data Sheet for Anchoring Buffer
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Publications
Lifei Wang, Rui Nie, Yankai Cai, Anqi Wang, Hanwen Zhang, Jiang Zhang, Jun Cai
bioRxiv (2023)
Abstract With the development of single-cell technology, many cell traits (e.g. gene expression, chromatin accessibility, DNA methylation) can be measured. Furthermore, the multi-omic profiling technology could jointly measure two or more traits in a single…
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Publications
Yawei Li, Yuan Luo
bioRxiv (2023)
Abstract Spatially resolved transcriptomics performs high-throughput measurement of transcriptomes while preserving spatial information about the cellular organizations. However, many spatially resolved transcriptomic technologies can only distinguish spots consisting of a mixture of cells instead of…
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Publications
Xi Jiang, Danni Luo, Esteban Fernández, Jie Yang, Huimin Li, Kevin W. Jin, Yuanchun Zhan, Bo Yao, Suhana Bedi, Guanghua Xiao, Xiaowei Zhan, Qiwei Li, Yang Xie
bioRxiv (2023)
Abstract The emerging field of spatially resolved transcriptomics (SRT) has revolutionized biomedical research. SRT quantifies expression levels at different spatial locations, providing a new and powerful tool to interrogate novel biological insights. An essential question…
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Publications
Charlotte R Wayne, Luca I Bremner, Travis E Faust, Violeta Durán-Laforet, Nicole Ampatey, Sarah J Ho, Philip A Feinberg, Panos Arvanitis, Bogoljub Ciric, Shannon L Delaney, Wendy Vargas-Deming, Susan Swedo, Vilas Menon, Dorothy P Schafer, Tyler Cutforth, Dritan Agalliu
bioRxiv (2023)
Abstract Group A Streptococcus (GAS) infections can cause neuropsychiatric sequelae in children due to post-infectious encephalitis. Multiple GAS infections induce migration of Th17 lymphocytes from the nose into the brain, which are critical for microglial activation, blood-brain…
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Publications
Meng Zhang, Xingjie Pan, Won Jung, Aaron Halpern, Stephen W Eichhorn, Zhiyun Lei, Limor Cohen, Kimberly A Smith, Bosiljka Tasic, Zizhen Yao, Hongkui Zeng, View ORCID ProfileXiaowei Zhuang
bioRxiv (2023)
Abstract In mammalian brains, tens of millions to billions of cells form complex interaction networks to enable a wide range of functions. The enormous diversity and intricate organization of cells in the brain have so…
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Publications
Zizhen Yao, Cindy T. J. van Velthoven, Michael Kunst, Meng Zhang, Delissa McMillen, Changkyu Lee, Won Jung, Jeff Goldy, Aliya Abdelhak, Pamela Baker, Eliza Barkan, Darren Bertagnolli, Jazmin Campos, Daniel Carey, Tamara Casper, Anish Bhaswanth Chakka, Rushil Chakrabarty, Sakshi Chavan, Min Chen, Michael Clark, Jennie Close, Kirsten Crichton, Scott Daniel, Tim Dolbeare, Lauren Ellingwood, James Gee, Alexandra Glandon, Jessica Gloe, Joshua Gould, James Gray, Nathan Guilford, Junitta Guzman, Daniel Hirschstein, Windy Ho, Kelly Jin, Matthew Kroll, Kanan Lathia, Arielle Leon, Brian Long, Zoe Maltzer, Naomi Martin, Rachel McCue, Emma Meyerdierks, Thuc Nghi Nguyen, Trangthanh Pham, Christine Rimorin, Augustin Ruiz, Nadiya Shapovalova, Cliff Slaughterbeck, Josef Sulc, Michael Tieu, Amy Torkelson, Herman Tung, Nasmil Valera Cuevas, Katherine Wadhwani, Katelyn Ward, Boaz Levi, Colin Farrell, Carol L. Thompson, Shoaib Mufti, Chelsea Pagan, Lauren Kruse, Nick Dee, Susan M. Sunkin, Luke Esposito, Michael J. Hawrylycz, Jack Waters, Lydia Ng, Kimberly A. Smith, Bosiljka Tasic, Xiaowei Zhuang, Hongkui Zeng
bioRxiv (2023)
Abstract The mammalian brain is composed of millions to billions of cells that are organized into numerous cell types with specific spatial distribution patterns and structural and functional properties. An essential step towards understanding brain…
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Publications
Milad R. Vahid, Erin L. Brown, Chloé B. Steen, Wubing Zhang, Hyun Soo Jeon, Minji Kang, Andrew J. Gentles & Aaron M. Newman
Nature Biotechnology (2023)
Abstract: Recent studies have emphasized the importance of single-cell spatial biology, yet available assays for spatial transcriptomics have limited gene recovery or low spatial resolution. Here we introduce CytoSPACE, an optimization method for mapping individual…
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Publications
Jiaqiang Zhu, Lulu Shang & Xiang Zhou
GenomeBiology (2023)
Abstract Spatially resolved transcriptomics (SRT)-specific computational methods are often developed, tested, validated, and evaluated in silico using simulated data. Unfortunately, existing simulated SRT data are often poorly documented, hard to reproduce, or unrealistic. Single-cell simulators…
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