Explore our new MERSCOPE FFPE Sample Prep Solution for high-quality spatial genomic analysis

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Vizgen is developing the next generation of genomics tools to expand on the capabilities of spatially resolved transcriptomics. Our technology will aide the acceleration of biological research and discovery to advance human health. Access supporting resources by selecting the category below.

Publications

Comparative analysis of MERFISH spatial transcriptomics with bulk and single-cell RNA sequencing

Jonathan Liu, Vanessa Tran, Venkata Naga Pranathi Vemuri, Ashley Byrne, Michael Borja, Snigdha Agarwal, Ruofan Wang, Kyle Awayan, Abhishek Murti, Aris Taychameekiatchai, Bruce Wang, George Emanuel, Jiang He, John Haliburton, Angela Oliveira Pisco, Norma Neff
bioRxiv doi:10.1101/2022.03.04.483068

Spatial transcriptomics extends single cell RNA sequencing (scRNA-seq) technologies by providing spatial context for cell type identification and analysis. In particular, imaging-based spatial technologies such as Multiplexed Error-Robust Fluorescence In Situ Hybridization (MERFISH) can achieve…

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Publications

Spatial transcriptomic reconstruction of the mouse olfactory glomerular map suggests principles of odor processing

I-Hao Wang, Evan Murray, Greg Andrews, Hao-Ching Jiang, Sung Jin Park, Elisa Donnard, Violeta Durán-Laforet, Daniel M. Bear, Travis E. Faust, Manuel Garber, Christina E. Baer, Dorothy P. Schafer, Zhiping Weng, Fei Chen, Evan Z. Macosko & Paul L. Greer
Nature Neuroscience (2022)

The olfactory system’s ability to detect and discriminate between the vast array of chemicals present in the environment is critical for an animal’s survival. In mammals, the first step of this odor processing is executed…

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Application & Technical Notes

smFISH Verification Technical Note

Overview: To generate the best data possible using our MERSCOPE Platform, researchers must ensure they are working with high-quality RNA samples. Unfortunately, RNA is easily degraded by RNases when samples are mishandled or treated in…

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Application & Technical Notes

Protein Co-Detection with MERSCOPE

Abstract: Spatially resolved transcriptomic imaging technologies such as Vizgen’s MERSCOPE TM platform allows massively multiplexed single-cell measurement in situ and have been instrumental for molecular and cell atlasing. However, cell types and states are not only…

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