Resources

Vizgen is developing the next generation of genomics tools to expand on the capabilities of spatially resolved transcriptomics. Our technology will aide the acceleration of biological research and discovery to advance human health. Access supporting resources by selecting the category below.

Application & Technical Notes

Tissue Clearing Sample Verification

Read this technical note to learn key points about tissue clearing for different types of human and mouse tissues. It also provides examples of different clearing conditions for human lung tissue sections.

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Application & Technical Notes

Cell Boundary Stainning On Different Tissue Types

Read technical note for information on how to select the optimal cell  boundary stain to use on different tissue types. It provides examples of cell boundary staining for various mouse and human tissue sections.

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Application & Technical Notes

Autofluorescence Quenching

Read this technical note to learn key points about autofluorescence background and autofluorescence quenching during the sample verification process. It provides examples of using the MERSCOPE Photobleacher to remove Lipofuscin Autofluorescence from human heart and […]

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User Guides

Cultured Cells Sample Preparation

This user guide explains how to properly prepare cultured cell samples to run on the MERSCOPE instrument and includes the protocol, materials, and technical tips. 

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User Guides

Sample Verification Kit

This user guide explains how to verify that the RNA quality after sample preparation will result in adequate MERFISH imaging quality with the MERSCOPE Instrument. It includes the protocol, materials, and examples. 

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Publications

Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH

Meng Zhang, Stephen W. Eichhorn, Brian Zingg, Zizhen Yao, Kaelan Cotter, Hongkui Zeng, Hongwei Dong & Xiaowei Zhuang
Nature volume 598, pages137–143 (2021)

A mammalian brain is composed of numerous cell types organized in an intricate manner to form functional neural circuits. Single-cell RNA sequencing allows systematic identification of cell types based on their gene expression profiles and […]

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