GABA receptive microglia selectively sculpt developing inhibitory circuits
Loic Binan, Ph.D, Klarman Cell Observatory, Broad Institute of Harvard and MIT
Emilia Favuzzi, Ph.D, Harvard Medical School and Broad Institute of Harvard and MIT
Microglia, the primary brain macrophages, regulate a plethora of processes that impact the organization of neural circuits, including synapse pruning. Watch this video to learn how researchers used MERFISH to demonstrate that distinct microglia differentially engage with specific synapse types during development.