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Vizgen is developing the next generation of genomics tools to expand on the capabilities of spatially resolved transcriptomics. Our technology will aide the acceleration of biological research and discovery to advance human health. Access supporting resources by selecting the category below.

Application & Technical Notes

Protein Co-Detection with MERSCOPE

Abstract: Spatially resolved transcriptomic imaging technologies such as Vizgen’s MERSCOPETM platform allows massively multiplexed single-cell measurement in situ and have been instrumental for molecular and cell atlasing. However, cell types and states are not only…

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Application & Technical Notes

Gel-free Sample Preparation Protocol

This technical note describes a MERSCOPE sample preparation protocol for cultured cells without the gel embedding steps, which simplifies the standard workflow and shortens the protocol by one day without compromising data quality. Additional sample…

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Application & Technical Notes

Molecular Atlassing with MERSCOPE

A New Spatial Transcriptomics Technique Accurately Reveals the Organization of The Mouse Brain Transcriptome This application note describes how the MERFISH Mouse Brain Receptor map was generated by MERSCOPE and demonstrates how the platform can…

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Application & Technical Notes

Tissue Clearing Sample Verification

Read this technical note to learn key points about tissue clearing for different types of human and mouse tissues. It also provides examples of different clearing conditions for human lung tissue sections.

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Application & Technical Notes

Cell Boundary Staining On Different Tissue Types

Read technical note for information on how to select the optimal cell  boundary stain to use on different tissue types. It provides examples of cell boundary staining for various mouse and human tissue sections.

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Application & Technical Notes

Autofluorescence Quenching

Read this technical note to learn key points about autofluorescence background and autofluorescence quenching during the sample verification process. It provides examples of using the MERSCOPE Photobleacher to remove Lipofuscin Autofluorescence from human heart and…

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