Innovations in Gene Expression Profiling: A Comparative Study

Introduction to Multiplexed In Situ Technologies
Researchers Hartman and Satija from the New York Genome Center and New York University have released a significant preprint entitled “Comparative Analysis of Multiplexed In Situ Gene Expression Profiling Technologies.” The study presents a comparative analysis of six in situ gene expression profiling methods.

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Key Finding

• Vizgen’s MERSCOPE datasets showed the best performance, with an optimal balance between sensitivity and specificity, and a large panel size of 483 genes.